Warning: include(/home/cbsac/public_html/pdf/exam_timetable/end-semester/dir.php): failed to open stream: No such file or directory in /home/cbsac/public_html/index.php on line 8

Warning: include(): Failed opening '/home/cbsac/public_html/pdf/exam_timetable/end-semester/dir.php' for inclusion (include_path='.:/usr/lib/php:/usr/local/lib/php') in /home/cbsac/public_html/index.php on line 8

Warning: session_start(): Cannot send session cookie - headers already sent by (output started at /home/cbsac/public_html/index.php:8) in /home/cbsac/public_html/libraries/joomla/session/session.php on line 658

Warning: session_start(): Cannot send session cache limiter - headers already sent (output started at /home/cbsac/public_html/index.php:8) in /home/cbsac/public_html/libraries/joomla/session/session.php on line 658
Sinjan Choudhary
Sinjan Choudhary
Assistant Professor
Sinjan Choudhury


  • PhD (Chemistry), Indian Institute of Technology Bombay, Mumbai (2012)
  • MSc (Biotechnology), Jawaharlal Nehru University, New Delhi (2008)


  • Assistant Professor : UM- DAE Centre for Excellence in Basic Sciences (January 2016 onwards)
  • Research Associate: UM- DAE Centre for Excellence in Basic Sciences (January 2013-December 2015)
  • Research Associate: Department of Chemistry, IIT Bombay (October 2012-December 2012)


  • Inhibition of protein fibrillation/aggregation by natural and synthetic products as potential inhibitors of aggregation-related diseases.
  • Biophysical investigation of biologically important systems: drug-protein and Protein-solvent Interactions.

Selected Publications

  • “Elucidation of the anticancer potential and tubulin isotype-specific interactions of β-sitosterol” Madhura Pradhan, Suri C, Sinjan Chudhary, Pradeep Kumar Naik, Manu Lopus. J. biomol. Struct. Dyn.(2016) 1-10. http://dx.doi.org/10.1080/07391102.2016.1271749.
  • “Synergistic Inhibition of Protein Fibrillation by Proline and Sorbitol: Biophysical Investigations” Sinjan Choudhary, Shreyada N Save, Nand Kishore, Ramakrishna V. Hosur. PlosOne (2016) 11(11):e0166487. doi:10.1371/journal.pone.0166487.
  • “Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations” Tejashree Mahaddalkar, Pradeep Kumar Naik, Sinjan Choudhary, Naresh Manchukonda, Srinivas Kantevari, Manu Lopus. J. biomol. Struct. Dyn. (2016) 1-10. doi:http://dx.doi.org/10.1080/07391102.2016.1222969.
  • “Rational Drug Design and Future Directions: Thermodynamic Perspective” Eva Judy, Sinjan Choudhary, Nand Kishore. Austin Biomol. Open Access. 1 (2016) 1003.
  • “Subtle Alterations in Microtubule Assembly Dynamics by Br-TMB-Noscapine Strongly Suppress Triple-Negative Breast Cancer Cell Viability Without Mitotic Arrest” Tejashree Mahaddalkar, Naresh Manchukonda, Sinjan Choudhary, Sanith Cheriyamundath, Neha Mohanpuria, Srinivas Kantevari, Manu Lopus, Chemistry Select 1 (2016) 4313 – 4319.
  • “Competitive binding of anticancer drugs 5-fluorouracil and cyclophosphamide with serum” Anu A Thoppil, Sinjan Choudhary, Nand Kishore, Biochimica et BiophysicaActa 1860 (2016) 917–929.
  • “Inhibition of insulin fibrillation by osmolytes: Mechanistic Insights”, Sinjan Choudhary, Nand Kishore, Ramakrishna V. Hosur, Scientific Reports (2016) 5:17599 | DOI: 10.1038/srep17599.
  • “Understanding thermodynamics of drug partitioning in micelles and delivery to proteins: Studies with naproxen, diclofenac sodium, tetradecyltrimethylammonium bromide, and bovine serum albumin”Paurnima Talele, Sinjan Choudhary, Nand Kishore, J. Chem.Thermodynamics 92 (2016) 182–190.
  • “Thermodynamic insights into drug-surfactant interactions: study of the interactions of naporxen, diclofenac sodium, neomycin, and lincomycin with hexadecytrimethylammonium-bromide by using isothermal titrationcalorimetry” Sinjan Choudhary, PaurnimaTalele, Nand Kishore, Colloids Surf B Biointerfaces 132 (2015) 313-321.
  • “Ribosomal Protein P2 from apicomplexan parasite, Toxoplasma gondii is intrinsically a molten globule” Pushpa Mishra, Sinjan Choudhary, Ramakrishna V. Hosur, Biophysical Chem. 200-201 (2015) 27-33.
  • “Molten globule nature of Plasmodium falciparum P2 homo-tetramer” Pushpa Mishra, Sinjan Choudhary, Sujoy Mukherjee, DishaSengupta, Shobhona Sharma, R.V. Hosur, Biochemistry and Biophysics Reports1 (2015) 97-107.
  • “Addressing mechanism of fibriliization/aggregation and its prevention in presence of osmolytes: spectroscopic and calorimetric approach. Sinjan Choudhary, Nand Kishore, PLOS ONE (2014) 9(8): e104600. doi:10.1371/journal.pone.0104600.
  • “Drug-protein interactions in micellar media: Thermodynamic aspects”, Sinjan Choudhary, Nand Kishore, J. Coll. Interface Sci. 413 (2014) 118-126.
  • “Effects of Hesperidin, a Flavanone Glycoside Interaction on the Conformation, Stability and Aggregation of Lysozyme: Multispectroscopic and Molecular Dynamic Simulation Studies”, Aditi Ratnaparkhi, Shivani A Mutthu, Sonali M Shiriskar, Raghuvir R S Pissurlenkar, Sinjan Choudhary, Basir Ahmad, J. biomol. Struct. Dyn.33 (2014) 1866-1879.
  • “Binding thermodynamics of the recognition of the antibiotic drug oxytetracycline with bovine serum albumin” NeelamKeswani, Sinjan Choudhary, Nand Kishore,J. Chem. Thermodyn. 58 (2013) 196-205.
  • “Unraveling the energetics and mode of the recognition of antibiotics tetracycline and rolitetracycline by bovine serum albumin”, Sinjan Choudhary, Nand Kishore,Chem. Biol. Drug Des. 80 (2012) 693-705.
  • Physico-chemical insights into the Binding of Diclofenac Sodium and CefotaximeSodium to Serum Albumin : Calorimetry and Spectroscopy”, Ruchika Sharma, Sinjan Choudhary, Nand Kishore, Eur. J. Pharm. Sci. 46 (2012) 435-445.
  • “Interactions of some short peptides with the osmolyte trimethylamine N-oxide inaqueous solution: physico-chemical insights” Sinjan Choudhary, Nand Kishore, J. Chem. Thermodyn. 52 (2012) 36-42.
  • “Thermodynamics of the interactions of a homologous series of some aminoacids with trimethylamine N-oxide: Volumetric, compressibility and calorimetricstudies”, Sinjan Choudhary, Nand Kishore, J. Chem. Thermodyn. 43 (2011)1541-1551.
  • “Interaction of weakly bound antibiotics, neomycin and lincomycin with serumalbumin : Biophysical approach”, NeelamKeswani, Sinjan Choudhary, Nand Kishore, J. Biochem. 148 (2010) 71-84.


UM-DAE Centre for Excellence in Basic Sciences
Health Centre, University of Mumbai,
Vidyanagari Campus, Kalina, Santacruz (East), Mumbai 400098, India.
Phone: 91-22-26524983
Fax: 91-22-26524982
General Enquiries: This email address is being protected from spambots. You need JavaScript enabled to view it.
Website Related: This email address is being protected from spambots. You need JavaScript enabled to view it.

About Us

CBS was set up by the Department of Atomic Energy and the University of Mumbai in 2007. CBS offers a 5 year integrated MSc program in Basic Sciences, with undergraduate teaching embedded in a postgraduate and research environment, for students who have completed 10+2 schooling or its equivalent.